You could, but how usable it will be depends on your TV.
On my LG, with 10 bit enabled, the TV goes into SDR BT2020 mode, which oversaturates color on all non-HDR content, making it look bad.
SDR BT2020 is 4:2:0 if I'm correct. My Philips 55/PUS6551 is set to 4:4:4/4:4:2 and for my untrained eye everything looks ok.