With resolution set to 3840x2160 @ 30FPS, I have not had this issue occur once in the last 2 weeks. The UI is more sluggish but its not slow. I always use 'adjust display refresh rate' on start/stop as well.
There's a problem with 60FPS output, how do we work out if its a Denon problem or a Pi problem though.... Could run directly into the TV for a while I suppose but this may be a false test as I won't be passing through DTS/Dolby HD etc.