Does LE have any realation with the moterbords chipset?

When installing LE into a USB stick and using it as a mediaplayer in a PC.

If using the same Nvidia graphicscard in 2 different motherboards with different chipset, will there be any differences in stability/performance when playing video files(1080p videos with HW on(vdpau) like H.264 and VC-1.)

Or does LE only rely on what CPU and GPU to perform regardles of what motherboard one is using.

ok, I was thinking of the Nvidia GT 730 and GTX 660 cards.....

OK, just wanted to know the thing about chipsets and the importance they play, now i know it doesent matter, thanks....