In the past exFAT and NTFS required "userspace" drivers that suffered from slow read/write performance. These days both of those filesystem types have native kernel drivers so performance isn't an issue. However both have reliability issues and NTFS notably can have issues that can only be corrected using chkdsk.exe on Windows. As such, the preferred format for Linux drives in LE is still ext4.
Ok, thanks for the quick reply. I run my disks(around 10TB) with NTFS, as I suspected that it does not work with exfat if files are larger than 4GB. The format you mention (ext4), is there a good guide on how to convert it? Kind regards, Thore