As for issues when switching profile, please provide a log (journalctl -u service.librespot)
Please check Aug 28 11:39:16 HTPC systemd: service.librespot.service: Service hold-off tim - Pastebin.com if you can find some hints for the issue while or after switching profile. Eventually there are some warnings, errors and fails.
In addition, I faced also an (greater) issue, when I upgraded to new kodi alpha via raybuntu's rb-leia6 => NO sound:
Sep 09 23:35:50 HTPC systemd: Started librespot. Sep 09 23:35:50 HTPC sh[791 - Pastebin.com
I can selected Kodi in Spotify as device, I can also play a song and Kodi displays the artist and song name on the top right (osd), BUT I there is no sound... On the configuration, there is no option "Kodi" in "Output". Under "Output" I am able only to select "Programs". So I selected "Programs" and via ALSA I changed to HDMI, which I have also selected in Kodi -> preferences -> system -> audio device.
Hoping for helping
Thanks for the work.