I'm not sure if the crash was due to using 2 monitors or having 1 4K and 1 HD monitor or if it was unrelated. I'd previous been scanning my NAS for TV programs and that took ages so not sure if I'd have had the crash anyway as a result of the really long scan.
When I've scanned movies, I'll reboot and see if it starts up ok. Then scan TV programs and reboot again.
Unrelated. The crash is due to data loss on your SD card, maybe you switched off without shutting down?
You were missing the file /storage/.kodi/userdata/profiles.xml which can sometimes go missing after an improper shutdown (and other reasons we're not entirely sure about), but when it does go missing then Kodi will crash on startup. Copying the file from the safe mode installation to your FAILED installation is the quickest fix and avoids a re-installation.