The core OS will downgrade without problems, but Kodi does not support downgrades so you'll end up with a bunch of add-ons at a higher and incompatible version and that can often have crashy consequences. Things like DB content will be fine as Kodi simply uses the older DB files that still on disk (or tables in MariaDB) and ignores the newer ones that correspond to new Kodi version.
Crossgrades between release and nightly versions are generally okay as long as Kodi API versions haven't changed. At this stage of the cycle things are stable on that front so it won't be an issue. If we're still in the pre-Alpha stages there are API bumps and that will cause issues from time to time.