Kind of "fixed" it by reducing the resolution (from something above 3000x) to 1920x1080.
Prehaps related to "upscaling"?
Check advice from here: https://wiki.libreelec.tv/configuration/4k-hdr#hdr
Using 1080p60 for GUI with 4k modes enabled is whitelist is recommended configuration. (You will get 4k resolution for video).
Running the GUI iat 4k is pointless (the skin texures are 1080p) and just makes kodi laggier.